Abstract Brain Derived Neurotrophic Factor (BDNF) signalling contributes to the formation. maturation and plasticity of Central Nervous System (CNS) synapses. Acute exposure of cultured brain circuits to BDNF leads to up-regulation of glutamatergic neuro-transmission. by the accurate tuning of pre and post synaptic features. https://annekleiners.shop/product-category/extend-shipping-contract/