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A naturally occurring Lgr4 splice variant encodes a soluble antagonist useful for demonstrating the gonadal roles of Lgr4 in mammals.

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Leucine-rich repeat containing G protein-coupled receptor 4 (LGR4) promotes the Wnt signaling through interaction with R-spondins or norrin. Using PCR amplification from rat ovarian cDNAs. we identified a naturally occurring Lgr4 splice variant encoding only the ectodomain of Lgr4. which was named Lgr4-ED. https://edgeclothing.shop/product-category/womens-tanks/
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